The Pediatric Health Outcomes Initiative (PHOI) is a prospective registry that will collect data from volunteers in pediatric practices on potential factors in acute and chronic diseases including breastfeeding, birth delivery route, vaccination status, and medications. The goal of PHOI is to provide a data registry that can be used by researchers in future studies to identify potential interventions to improve overall pediatric outcomes.

The Pediatric Health Outcomes Initiative is a prospective registry that seeks to recruit 5,000 newborns (< 30 days old), and will follow them for 18 years to determine if vaccination status plays any role in the development of either acute or chronic diseases amongst the children in the United States. 

Over the last 40 years, there has been an increase in the number of children diagnosed with multiple conditions, including asthma, eczema, allergies, attention deficit disorder (ADD), and autism. Some physicians and researchers have questioned if the increase in both the number of vaccines the pregnant mother receives, and the number of childhood vaccines, plays any role in the current state of our children’s health.  In 1983, the Centers for Disease Control (CDC) vaccine schedule recommended children ages 0-18 receive a total of 11 vaccines,
​five of which were given during the first 13 months.   
In 2017, that number had increased to 55 vaccines, with 28 administered in the first 13 months.

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