phoi
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Overview

The Pediatric Health Outcomes Initiative is a prospective registry that seeks to recruit 5,000 newborns (< 30 days old), and will follow them for 18 years.  The goal is to determine if breastfeeding, birth delivery route, vaccination status, medications, or other factors play any role in the development of either acute or chronic diseases in children in the United States. Over the last 40 years, there has been an increase in the number of children diagnosed with both acute and chronic conditions, including asthma, eczema, allergies, attention deficit disorder (ADD), and autism. Some physicians and researchers have questioned whether any of several factors play a role in the current state of our children’s health. The PHOI registry seeks to collect prospective data to help answer this question.

Information Collected

If a parent decides to participate in the registry, they will complete an electronic questionnaire that will ask about:
  • The mother's health
  • The family's health

The mother will be asked to answer additional questions about the pregnancy, including, but not limited to:
  • Medications or dietary supplements 
  • Vaccinations she received 
  • Fertility treatments  (if applicable)
  • Dietary habits 
  • Exercise habits
  • Alcohol or drug use
  • Birth questions, like route of delivery (C-section or vaginal), cord clamping, and circumcision (if applicable)


At the time of her baby's first birthday, the mother or caregiver will complete a questionnaire that asks about:
  • Breastfeeding status
  • Baby's use of medications and dietary supplements
  • Vaccines received
  • Baby's adverse reactions to medications or vaccines
  • Baby's overall health during their first 12 months


The research staff will collect data every two years from each subject's medical record to record the following:
  • Diagnosis codes
  • Vaccines administered
  • Medications prescribed
  • Dietary supplements used

PHOI will track the administration of vaccines as decided by parents based upon informed consent. The goal of the registry is to provide data that can be studied to examine if there is any difference in the frequency children are diagnosed with either acute or chronic illnesses based on breastfeeding, birth delivery route, vaccination status, medications, and other factors.
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